| 书目名称 | Spatial Genome Organization |
| 副标题 | Methods and Protocol |
| 编辑 | Tom Sexton |
| 视频video | |
| 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microscopy. Finally, in order to be able to ask functional questions about the role of spatial chromatin organization in genomic control, the last section provides methods for acute manipulations of chromatin architecture. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Spatial Genome Organization: Methods and Protocols. is an ideal resource for researchers searching for the best techniques to address their own specific research ques |
| 出版日期 | Book 2022 |
| 关键词 | Chromosome conformation capture; Chromatin architecture; Nuclear environment; Targeted Hi-C; Genome topo |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-0716-2497-5 |
| isbn_softcover | 978-1-0716-2499-9 |
| isbn_ebook | 978-1-0716-2497-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 19:41:08
