| 书目名称 | Sparking Signals |
| 副标题 | Kinases as Molecular |
| 编辑 | G. Baier,B. Schraven,A. von Bonin |
| 视频video | |
| 概述 | Internationally well known experts presented their most recent findings on the fast developing kinase field.Outstanding interest for basic researchers and pharmaceutical industry |
| 丛书名称 | Ernst Schering Foundation Symposium Proceedings |
| 图书封面 |  |
| 描述 | .Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.. |
| 出版日期 | Conference proceedings 2008 |
| 关键词 | Cellular Signalling; Drug Finding; Immune-modulation; Kinase Inhibitors; Proteomics; Translation; metaboli |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-540-73501-4 |
| isbn_softcover | 978-3-642-09262-6 |
| isbn_ebook | 978-3-540-73501-4Series ISSN 0947-6075 |
| issn_series | 0947-6075 |
| copyright | Springer-Verlag Berlin Heidelberg 2008 |
发表于 2025-3-21 17:30:46
