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Titlebook: Signal Transduction Mechanisms; Junor A. Barnes,Haldane G. Coore,Rajendra K. Sharm Book 1995 Kluwer Academic Publishers 1995 ATP.Amino aci

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PEST sequences in calmodulin-binding proteins,ain PEST sequences and are susceptible to proteolysis by endogenous neutral proteases such as calpain I and calpain II. In this report, we discuss the functions of PEST sequences in calmodulin-binding proteins and assess the correlation between calmodulin-binding proteins and PEST sequences.
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Effects of pyruvate on pyruvate dehydrogenase kinase of rat heart,edium. When carbonyl cyanide m-chlorophenylhydrazone (CCCP) instead of rotenone was present, pyruvate at 1 mM concentration stimulated PDHK from hearts of fed animals but was without effect at 10 mM. When .PDC or PDC from hearts of starved animals was incubated at 30°C for 30 min, inhibition of PDHK by pyruvate was restored.
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Protein tyrosine phosphorylation in cardiovascular system,cute action of growth factors and vasoactive peptides on smooth muscle contractility. This review will briefly summarize the recent work on vasoactive peptide- mediated protein tyrosine phosphorylation in cardiovascular tissues and its potential functional significance.
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PEST sequences in calmodulin-binding proteins, in proline (P), glutamate (E), serine (S) and threonine (T). These designated PEST sequences are believed to be putative intramolecular signals for rapid proteolytic degradation. Calmodulin is a ubiquitous, 17 kDa, acidic Ca.-binding protein which plays an important role in the regulation of many p
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High molecular weight calmodulin-binding protein is phosphorylated by calmodulin-dependent protein dependent protein kinase was originally discovered when the total CaM-binding protein fraction from cardiac muscle was loaded on a gel filtration column. The CaM-dependent protein kinase was shown by gel filtration chromatography to have an apparent molecular mass of 36,000 daltons. The CaM-dependen
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