| 书目名称 | Signal Transduction Mechanisms | | 编辑 | Junor A. Barnes,Haldane G. Coore,Rajendra K. Sharm | | 视频video | | | 丛书名称 | Developments in Molecular and Cellular Biochemistry | | 图书封面 |  | | 描述 | This volume contains the proceedings of an InternationalSymposium on `Second Messenger Systems - Molecular, Cellularand Behavioural Aspects‘, which was held at Tobago on June16-17, 1994. .The interaction of an extracellular agonist (First Messenger) with itsplasma membrane receptor leads to the transmission of a signal acrossthe cell membrane and results in the production and/or activation ofother signalling molecules (Second Messengers). These SecondMessengers control the action of many protein kinases and proteinphosphatases and so lead to cellular responses. Although thebiochemical basis of the transduction of signals in the mainsignalling systems in eukaryotic cells is probably largely known,intensified research is ongoing in the following areas: the discoveryof specific substrates for many protein kinases, elucidation of thebiological significance of the differential tissue expression andheterogeneity of many signalling proteins, and the unravelling ofdiverse interactions (such as signal potentiation, synergism,antagonism and neuronal co-transmission) between signalling systems.As knowledge from such studies accumulates, it is becoming clear thatthe `cross talk‘ interactions b | | 出版日期 | Book 1995 | | 关键词 | ATP; Amino acid; Calcium; Glycogen; Nucleotide; Translation; proteins | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4615-2015-3 | | isbn_softcover | 978-1-4613-5833-6 | | isbn_ebook | 978-1-4615-2015-3 | | copyright | Kluwer Academic Publishers 1995 |
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