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Titlebook: Short Course Breast Radiotherapy; A Comprehensive Revi Douglas W Arthur,Frank A. Vicini,Atif J. Khan Book 2016 Springer International Publi

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APBI: History, Rationale, and Controversiesing breast conservation instead of mastectomy, investigators began to study alternative approaches that could achieve comparable cancer outcomes while reducing the burden of care imposed by the 4–6 weeks of daily radiotherapy delivery post lumpectomy (Fig. 1.1). Partial breast irradiation, that is,
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New York University Experience and Prone Positioning of hypofractionated regimens. Over more than a decade, several prospective trials have investigated the optimal prescription dose/fractionation to the whole breast, the timing of lumpectomy bed boost, and the efficacy of prone partial breast irradiation.
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United Kingdom Experience: Clinical Trial Evolution, Techniques, Data, and Toxicity15 fractions is gentler than the historical 50 Gy in 2.0 Gy fractions. Where the heart is concerned, the priority is protection regardless of fractionation regimen. Large-breasted women benefit from hypofractionation by virtue of less severe acute skin reactions and fewer consequential late effects,
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Patient Selection for Accelerated Partial Breast Irradiation (APBI) will continue over the ideal patient population to treat with APBI. While the presently available guidelines are imperfect, they were created to ensure conservative patient management and safety. It is suggested that these guidelines should be followed by practitioners until replaced with more curr
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