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Titlebook: Sepsis and Organ Dysfunction; Bad and Good News on A. E. Baue,G. Berlot,J.-L. Vincent Conference proceedings 2001 Springer-Verlag Italia 20

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Bad and Good News in Pathophysiology, Prevention, and Management of Sepsis,o-inflammatory and counter-regulatory molecules. Ascribing qualifiers of benefit or harm to any inflammatory mediator (e.g. IL-1 or TNR) depends on the clinical context and the net effects of change over time during an infection.
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Epidemiology of Infections in ICUs: Where Are We?,relative high incidence of infections, rates of which are higher than 40% as reported in some prevalence studies [2, 3]. This percentage is 5–10 times higher when compared with the infections in patients admitted in the normal wards; furthermore, in some hospitals of United States, recurrence of inf
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Neutrophil Defensins in Lung Inflammation,he defensins, are one component of innate immunity. Defensins have well documented bactericidal properties. In addition, recent studies have suggested that defensins have other, pro-inflammatory, activities. Furthermore there is evidence that defensins can damage host tissue, and may contribute to t
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Bad and Good News in Pathophysiology, Prevention, and Management of Sepsis,d often fail to account for the redundancy and interdependence of inflammatory responses. The net response elicited by a cytokine on a target cell is not an isolated event, but depends on the state of cell-associated cytokine receptors (which may be up or down-regulated) and the presence of other pr
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