书目名称 | Self-Assembling Peptide Systems in Biology, Medicine and Engineering | 编辑 | Amalia Aggeli,Neville Boden,Shuguang Zhang | 视频video | | 图书封面 |  | 描述 | One ofthe major drivers in biological research is the establishment ofstructures and functions of the 50,000 or so proteins in our bodies. Each has a characteristic- dimensional structure, highly "ordered" yet "disordered"! This structure is essential for a protein‘s function and, significantly, it must be sustained in the competitive and complex environment of the living cell. It is now being recognised that when a cell loses control, proteins can se- assemble into more complex supermolecular structures such as the amyloid fibres and plaques associated with the pathogenesis of prion (CJD) or age-related (Alzheimer‘s) diseases. This is a pointer to the wider significance of the self-assembling properties of polypeptides. It has been long known that, in silk, polypeptides are assembled into- sheet structures which impart on the material its highly exploitable properties of flexibility combined with high tensile strength. But only now emerging is the recognition that peptides can Self-assemble into a wide variety of non-protein-like structures, including fibrils, fibres, tubules, sheets and monolayers. These are exciting observations and, more so, the potential for materials and medi | 出版日期 | Book 2002 | 关键词 | Biopolymer; Lipid; Tissue Engineering; biomedical engineering; membrane proteins; polymer; proteins; thermo | 版次 | 1 | doi | https://doi.org/10.1007/0-306-46890-5 | isbn_softcover | 978-90-481-5740-2 | isbn_ebook | 978-0-306-46890-2 | copyright | Springer Science+Business Media Dordrecht 2002 |
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