Titlebook: Seeking Molecular Biomarkers for Schizophrenia Using ROC Analysis; Margareth Borges Coutinho Gallo Book 2024 The Editor(s) (if applicable)

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Book 2024by dynamic systemic biological changes that unfold over the course of the disease. Thus far, the diagnosis is solely based on symptoms, which may be rather subjective, moving research toward the search for SSD biomarkers. This book presents a summary of the main hypotheses that have evolved over tim

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Hypotheses of the Pathophysiology of Schizophrenia Spectrum Disorders, neuroendocrine, immune-inflammatory, nitrosative/oxidative stress, metabolic, and gut microbiota-brain axis—with the aim of showing the most relevant research carried out in the last twelve years to develop predictive or diagnostic models based on these biomarkers.

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Step-by-Step Guide to Building a Diagnostic Model Using MetaboAnalyst,oping a diagnostic model using molecular biomarkers, the author has crafted a tutorial. This comprehensive guide details each step with examples, explanations of graph interpretations, and commentary on the essential concepts needed for a successful analysis.

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Hypotheses of the Pathophysiology of Schizophrenia Spectrum Disorders,y dynamic systemic biological changes that unfold over the course of the disease. In this chapter, we present a summary of the main hypotheses that have evolved over time to explain the pathophysiology of SSD and that have driven the discovery of associated biomarkers—neurotrophic, neurotransmitter,

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Immune, Inflammatory and Oxidative Stress-Related Biomarkers,oxidative stress has been widely considered. Despite this, the controversy persists regarding the effectiveness of utilizing biomarkers associated with these processes for diagnosing SSD patients. This chapter reviews research conducted over the past 12 years (2011–2023), employing the receiver oper

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