| 书目名称 | Seeking Molecular Biomarkers for Schizophrenia Using ROC Analysis | | 编辑 | Margareth Borges Coutinho Gallo | | 视频video | | | 概述 | Summarizes the main hypotheses of the pathophysiology of SSD and that have driven associated biomarkers discovery.Highlights research from the last twelve years to develop predictive, diagnostic, ther | | 图书封面 |  | | 描述 | .Schizophrenia Spectrum Disorders (SSD) manifest multidimensionally, presenting a syndromic nature with several symptomatic domains. These are driven by dynamic systemic biological changes that unfold over the course of the disease. Thus far, the diagnosis is solely based on symptoms, which may be rather subjective, moving research toward the search for SSD biomarkers. This book presents a summary of the main hypotheses that have evolved over time to explain the pathophysiology of SSD and that have driven the discovery of associated biomarkers: neurotrophic, neurotransmitter, neuroendocrine, immune-inflammatory, nitrosative/oxidative stress, metabolic, and gut microbiota-brain axis. The book shows the most relevant research carried out in the last twelve years to develop predictive, diagnostic, theranostic or transdiagnostic models based on these biomarkers using the receiver operating characteristic curve (ROC) analysis. Chapters also discuss how the literature has addressed the development and/or addition of new discriminatory biomarkers to achieve robust and successful results. The book is rounded out with a step-by-step explanation on how to work on the MetaboAnalyst platform, | | 出版日期 | Book 2024 | | 关键词 | Schizophrenia Spectrum Disorders (SSD); SSD Biomarkers; Pathophysiology of SSD; Metaboanalyst platform; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-59028-3 | | isbn_softcover | 978-3-031-59585-1 | | isbn_ebook | 978-3-031-59028-3 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 19:26:44
