Titlebook: Schizophrenia; Methods and Protocol Leyre Urigüen,Rebeca Díez-Alarcia Book 2023 The Editor(s) (if applicable) and The Author(s), under excl

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María Recio-Barbero,Noemi Losada-León,Oihane Mentxaka,Janire Cabezas-Garduño,Rafael Segarra organ or hematopoietic stem cell transplant. Chronic inflammation impacts negatively on male reproductive endpoints, so immunosuppressant therapy can produce improvements. Corticosteroids have been used to treat antisperm antibodies and even as an empirical treatment for male infertility in general

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Oihane Mentxaka,María Recio-Barbero,Janire Cabezas-Garduño,Rafael Segarranegatively impact on male reproduction and these effects are of increasing concern. People world-wide are using more medications than in the past, including men of childbearing age. In addition, men are fathering children later in life than previously, which is associated with greater medication use

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lobal, regional and national levels.Includes supplementary m.Since the late 1990s, megaconferences in the water-related sectors have become regular occurrences. The latest one, in Mexico City, in March 2006, is estimated to have cost a total of $205 million, and had 19,000+ participants. In spite of

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Neuropsychological and Functional Assessment of Cognitive Impairments in Schizophrenia,t of schizophrenia. Here we describe the main aspects to consider before, during, and after the neuropsychological assessment of main cognitive domains affected in schizophrenia, from a research perspective toward clinical practice.

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A Novel Method to Estimate Levels of Receptors Using an Allosteric Modulator: Focus on Muscarinic Md density of radioligand binding to a receptor in tissue or on cells. In addition it describes an innovative step forward in using radioligand binding assays to measure levels of muscarinic M1 receptors in human postmortem CNS, using both membrane binding and in situ radioligand binding. These examp

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Enhanced Bystander BRET (ebBRET) Biosensors as Biophysical Tools to Map the Signaling Profile of Ne-reaching applications in detecting physiologically relevant protein-protein interactions. The recently developed enhanced bystander BRET (ebBRET) biosensors have made it possible to rapidly determine the signaling profile of a series of ligands across a large number of GPCRs and their signaling rep

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CRISPR/Cas9 as a Simple Technique for the Generation of Murine Knockout Models for Neuropsychiatricchiatric disorders are thought to be triggered by multiple factors, and furthermore, the genetic component of schizophrenia is highly complex. The edition of one single gene for mimicking some of the symptoms of the disorder could cause unintended mutations that could influence animal’s behavior mak

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Evaluation of Sensorimotor Gating Deficits in Mice Through Prepulse Inhibition (PPI) of the Startlelse inhibition is considered a translational indicator of sensorimotor gating deficits present in schizophrenia patients and is crucial in the characterization of animal models of schizophrenia-like behaviors. Hallucinogenic drugs acting through 5-HT2A receptors, such as psilocybin, lysergic acid di