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Titlebook: Special Issue on Emerging Bacterial Toxins; Klaus Aktories,Ingo Just Book 2005 The Editor(s) (if applicable) and The Author(s), under excl

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书目名称Special Issue on Emerging Bacterial Toxins
编辑Klaus Aktories,Ingo Just
视频video
丛书名称Reviews of Physiology, Biochemistry and Pharmacology
图书封面Titlebook: Special Issue on Emerging Bacterial Toxins;  Klaus Aktories,Ingo Just Book 2005 The Editor(s) (if applicable) and The Author(s), under excl
出版日期Book 2005
关键词Anthrax toxins; Clostridial toxins; Helicobacter pylori cytotoxin; Pasteurella multocida toxin; Pseudomo
版次1
doihttps://doi.org/10.1007/b138634
isbn_ebook978-3-540-27115-4Series ISSN 0303-4240 Series E-ISSN 1617-5786
issn_series 0303-4240
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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Rho-modifying C3-like ADP-ribosyltransferases,uctures of C3 exoenzymes are available, allowing novel insights into the structure-function relationships of these exoenzymes. Because ADP-ribosylation specifically inhibits the biological functions of the low-molecular mass GTPases, C3 exoenzymes are established pharmacological tools to study the c
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CNF and DNT,ne cells, phagocytosis by macrophages, secretion of cytokines, maintenance of epithelial barrier functions and others. With respect to these functions, it is not surprising that many bacterial protein toxins, which are important virulence factors and causative agents of human and/or animal diseases,
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ExoS and ExoT,al ADP-ribosylation domains. The Rho GAP activities of ExoS and ExoT appear to be biochemically and biologically identical, targeting Rho, Rac, and Cdc42. Expression of the RhoGAP domain in mammalian cells results in the disruption of the actin cytoskeleton and interference of phagocytosis. Expressi
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