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Titlebook: Resistance to Tyrosine Kinase Inhibitors; Daniele Focosi Book 2016 Springer International Publishing Switzerland 2016 Cancer Cells.Inhibit

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发表于 2025-3-21 18:45:25 | 显示全部楼层 |阅读模式
书目名称Resistance to Tyrosine Kinase Inhibitors
编辑Daniele Focosi
视频video
概述The volume will provide readers with a primer on tyrosine kinase signaling and its importance in cancer.The reader will be first introduced to common denominators of small-molecule and antibody-derive
丛书名称Resistance to Targeted Anti-Cancer Therapeutics
图书封面Titlebook: Resistance to Tyrosine Kinase Inhibitors;  Daniele Focosi Book 2016 Springer International Publishing Switzerland 2016 Cancer Cells.Inhibit
描述.The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors..
出版日期Book 2016
关键词Cancer Cells; Inhibitors; Kinase; Small-Molecular Inhibitors; Tyrosine
版次1
doihttps://doi.org/10.1007/978-3-319-46091-8
isbn_softcover978-3-319-83438-2
isbn_ebook978-3-319-46091-8Series ISSN 2196-5501 Series E-ISSN 2196-551X
issn_series 2196-5501
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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发表于 2025-3-21 23:45:50 | 显示全部楼层
2196-5501 to common denominators of small-molecule and antibody-derive.The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of re
发表于 2025-3-22 03:36:01 | 显示全部楼层
Tyrosine Kinase Signaling Pathways in Normal and Cancer Cells,rcinogenesis. In this chapter, we will discuss signaling pathways engaging PTKs and their implications in the initiation and progression of several human malignancies. We will point out the principal cancer cell types known to be candidates for tyrosine kinases inhibitors (TKIs)-or monoclonal antibodies-based targeted therapies.
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Resistance to Tyrosine Kinase Inhibitors in Different Types of Solid Cancer,ould facilitate the identification of actionable targets and development of new combination therapies for cancer patients. Although extensive studies have been applied to elucidate the underlying mechanisms, evidence is far from enough to establish a well-defined picture to correct resistance. The u
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