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Titlebook: Research in Chronic Viral Hepatitis; W. H. Gerlich Conference proceedings 1993 Springer-Verlag/Wien 1993 antibody.antigen.cancer.cell.hepa

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Molecular basis of the diversity of hepatitis B virus core-gene productsnic and biophysical properties which distinguish the HBeAg from the HBcAg are primarily due to the 10 amino acid long portion of the HBeAg leader sequence that remains attached to the HBeAg after cleavage.
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In vitro culture systems for hepatitis B and delta virusestro culture system for the hepatitis B virus (HBV) was a considerable impediment to the study of its life cycle at the cellular and molecular levels. However, it did not prevent its isolation and molecular cloning. Such has been the case also for the hepatitis delta virus (HDV), the genome of which
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Chronic infection in woodchucks infected by a cloned hepatitis delta virusthological signs of acute and chronic HDV infection. HDV-RNA and hepatitis delta antigen (HDAg) were detected in serum by slot-blot hybridization and by western blot five weeks after inoculation. Liver biopsy specimens collected at 8th week post inoculum were positive for HDV-RNA. Anti-HDV antibodie
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Susceptibility of human liver cell cultures to hepatitis C virus infectionated with serum samples from two HCV-infected patients. Viral RNA sequences were detected by polymerase chain reaction, using primers specific for the 5′ noncoding region of HCV, in extracts prepared from the hepatocyte cultures as early as 5 days after inoculation. Virus was also released from the
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Characterization of the endogenous protein kinase activity of the hepatitis B viruslates serine residue(s) localized within the lumen of the particle. By using purified, liver-derived core particles, we characterized the protein kinase activity in the presence of different ions and inhibitors. Controls were performed with cAMP-dependent protein kinase (PKA) and protein kinase C (P
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