Titlebook: Repair and Regeneration of the Nervous System; Report of the Dahlem J. G. Nicholls Conference proceedings 1982 Dr. S. Bernhard, Dahlem Konf

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Regeneration of Synapses,throughout life in uninjured animals. The sites at which new synapses form, their maturation, and their fate are all regulated by an exchange of morphogenetically important information between pre- and post-synaptic partners. Factors already known to participate in this exchange at the skeletal neur

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Recovery Mechanisms in the Mammalian Brain, and by results from animal experiments. Emphasis is laid on the evidence that recovery processes are gated by mechanisms of selective attention. Results are reported from developmental work which demonstrates that experience-dependent modifications of neuronal response properties are also controlle

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Adaptive and Maladaptive Regeneration in the Spinal Cord,then find and re-innervate their appropriate postsynaptic targets. Although spinal axons can regenerate, the formation of a dense glial scar at the lesion effectively blocks regrowth in adult mammals. However, implantation of peripheral nerve grafts between the cut ends of the cord has been effectiv

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Temporal Changes After Spinal Cord Injury,ems - reveal considerable complexity in the changes which occur over time. Some reflexes exhibit depression soon after transection, while others are enhanced. In the period 10–30 days after transection, many systems show enhanced function. There is substantial variability in events occurring at long

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Neural Development: Implications for Recovery from Injury,ter injury. In considering this question we discussed the developmental events leading to the original establishment of cellular elements and their connections within the CNS in order to determine a) what lessons relevant to regeneration can be learned from development, and b) whether it might ever

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Early Responses to Neural Injury,ses both in the axotomized neurons themselves and in surrounding or connected uninjured neurons in animals as diverse as leeches and man. The responses observed are considered in the light of what is now known about cellular mechanisms involved in the normal development and maintenance of neurons, i