| 书目名称 | Relaxing and Contracting Factors | | 副标题 | Biological and Clini | | 编辑 | Paul M. Vanhoutte | | 视频video | http://file.papertrans.cn/827/826311/826311.mp4 | | 丛书名称 | The Endothelium | | 图书封面 |  | | 描述 | It is an exciting task to be the editor of the first monograph covering a new area of the biomedical sciences. Since the first report in 1980 by Robert Furchgott and colleagues (see Chapter 1) of the evidence of endothelium-dependent relaxation in isolated arteries, there are ever increasing numbers of vascular physiologists and pharmacologists who are scraping away the endothelium to look into its role in cardiovascular con trol. And the more one looks, the more one discovers. Not only is the list of substances that can induce endothelium-dependent relaxations im pressively long, but these intriguing cells can also secrete vasoconstrictor substances. The ability of the endothelium to modulate the degree of con traction of the underlying smooth muscle is an ancestral property of the blood vessel wall, illustrating the logic of nature, since the endothelial cells are located in the best possible strategic location to continuously monitor the properties (chemical or physical) of the blood. And more and more data emerge suggesting that in several cardiovascular diseases per turbations in endothelium-dependent responses are one of the early signs of the abnormal process. Thus, the | | 出版日期 | Book 1988 | | 关键词 | Dilatation; Drogen; blood vessel; cardiovascular; cells; endothelium; hypertension; physiology; smooth muscl | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4612-4588-9 | | isbn_softcover | 978-1-4612-8939-5 | | isbn_ebook | 978-1-4612-4588-9 | | copyright | The Humana Press Inc. 1988 |
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