Titlebook: Relaxin and Related Peptides; Alexander I. Agoulnik Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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The Vascular Actions of Relaxin,vestigations of maternal vascular adaptations to pregnancy in which the hormone is turning out to be an important mediator. This chapter is separated into three parts. In Part 1, we discuss relaxin in the setting of normal vascular function and focus on systemic hemodynamics and arterial mechanical

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Relaxin-Like Ligand-Receptor Systems Are Autocrine/Paracrine Effectors in Tumor Cells and Modulate tein coupled receptors LGR7 (relaxin receptor) or LGR8 (relaxin/INSL3 receptor). These relaxin-like ligand-receptor systems modulate cellular functions and activate signaling cascades in a tumor-specific context leading to changes in tumor cell proliferation, altered motility/migration and enhanced

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Relaxin-Family Peptide and Receptor Systems in Brain: Insights from Recent Anatomical and Functionaammalian parturition. More recent research, however, has clearly indicated additional physiological and/or therapeutic roles for relaxin in the cardiovascular, renal and respiratory systems (see other Chapters); while a few studies have also described possible physiological effects of relaxin in the

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0065-2598 axin research.Relaxin and Related Peptides discusses the established paradigms, the contradictions, and the most recent findings and future directions in the field of relaxin research. The array of diverse topics are highlighted, ranging from evolution of relaxin family peptides and receptors to the

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Relaxin-Like Ligand-Receptor Systems Are Autocrine/Paracrine Effectors in Tumor Cells and Modulate d metastasis. This review presents recent new findings and emphasises the important functions of the relaxin/INSL3 ligand-receptor system as novel autocrine/paracrine effectors influencing tumor progression and tissue invasiveness.