Titlebook: Regulatory Toxicology; Franz-Xaver Reichl,Michael Schwenk Reference work 20141st edition Springer-Verlag Berlin Heidelberg 2014 environmen

Etching

Incumbent

Working Areas of Regulatory Toxicology make regulatory decisions independently of one another. Consistency of decision involves harmonizing; thus, cross-border cooperation of toxicologists and other regulatory affairs specialists is essential.

胶水

National and International Collaboration in Regulatory Toxicologyowing the principles of sustainable development with the goal of a better quality of life of all people. A number of international bodies and authorities promote the sound management of chemicals at national and international level, some of which are described in this chapter.

Paradox

真

Examination of Organ Toxicity organs and tissues that have a physiological dependence on the primary target. The assessment of organ toxicity must therefore take into account the complex physiological interdependence of tissues and organs within the body.

朝圣者

AWE

Toxicokinetic Testsles of the parent substance, its metabolites, or degradation products. Accordingly, toxicokinetic data provide indispensable estimates for systemic and organ-specific substance burdens and contribute significantly to the interpretation of toxicological data and their significance for humans.

不可接触

Forsake

争吵

Aims and Mission of Regulatory ToxicologyOS) can be calculated by comparing the NOAEL with the human exposure. In general, up to now the risk of genotoxic carcinogens at a certain exposure concentration is estimated by linear extrapolation of the dose–response curve. Additional information for the evaluation of the human relevance of exper