书目名称 | Recombination and Meiosis | 副标题 | Models, Means, and E | 编辑 | Richard Egel,Dirk-Henner Lankenau | 视频video | | 概述 | Together with the preceding volume in the series, this book covers all major aspects of meiotic research.The chapters are written by expert researchers who significantly contributed to the progress in | 丛书名称 | Genome Dynamics and Stability | 图书封面 |  | 描述 | .Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm – in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeast | 出版日期 | Book 2008 | 关键词 | Chromosom; DNA; DNA Double-Strand Breaks; Homolog Synapsis; Meiosis, Evolution of; biochemistry; chromosom | 版次 | 1 | doi | https://doi.org/10.1007/978-3-540-68984-3 | isbn_softcover | 978-3-642-08850-6 | isbn_ebook | 978-3-540-68984-3Series ISSN 1861-3373 Series E-ISSN 1861-3381 | issn_series | 1861-3373 | copyright | Springer-Verlag Berlin Heidelberg 2008 |
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