书目名称 | Recent Advances in Nervous System Toxicology | 编辑 | Corrado L. Galli,Luigi Manzo,Peter S. Spencer | 视频video | | 丛书名称 | NATO Science Series A: | 图书封面 |  | 描述 | This volume addresses some facets of the adverse actions of chemical agents on the central and peripheral nervous systems in developing and mature states. Some of the effects of these chemicals are short-lasting and rapidly reversible; others, especially those that cause structural damage to the nervous system, may result in permanent damage to the organism. The nervous system has several levels of vulnerability to toxic substances. Some substances perturb ion channels or synaptic mechanisms required for the orderly transfer of electrochemical information within the nervous system. Others disrupt sites required for the maintenance of cellular integrity, and these variably result in degenerative responses of neurons and myelinating cells. Further sites of vulnerability include the delicate neural vasculature and neurohumeral mechanisms responsible for physiological homeostasis. The science of neurotoxicology inevitably is a multidisciplinary endeavor, with contributions from biochemistry, physiology, morphology and behavior, to name a few. The challenge is to apply appropriate techniques to investigate neurotoxic phenomena. The first logical step in this analysis is to determine fro | 出版日期 | Conference proceedings 1988 | 关键词 | Nervous System; biochemistry; neurobehavioral assessment; neurons; neurotoxicology; physiology | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4613-0887-4 | isbn_softcover | 978-1-4612-8229-7 | isbn_ebook | 978-1-4613-0887-4 | copyright | Plenum Press, New York 1988 |
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