书目名称 | Recent Advances in NGF and Related Molecules |
副标题 | The Continuum of the |
编辑 | Laura Calzà,Luigi Aloe,Luciana Giardino |
视频video | http://file.papertrans.cn/823/822899/822899.mp4 |
概述 | Each chapter is contributed by renowned scientists in the field.Includes highlights of pioneering research on NGF in various areas of biomedicine and neuroscience.Focuses on the non-canonical function |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .More than fifty years after its initial discovery by Rita Levi Montalcini and Stanley Cohen and the proposal of the neurotrophic theory, nerve growth factor (NGF) has become the prototype of a family of biologically active molecules called neurotrophic factors (NTFs)..This book addresses important advances in NTF research, from basic science to clinical medicine. It focuses mainly on NGF, but also includes individual chapters dealing with the brain-derived neurotrophic factor (BDNF) and ligands of the glial cell line-derived neurotrophic factor (GDNF) family, which have attracted increasing interest in the neuroscience community because of their diverse effects in the normal and diseased brain..In the first part of the book, the authors provide the necessary background for the following chapters and discuss the basic mechanisms and pathways of NGF signal transduction. In the following sections, they then examine the regenerative activity and neuroprotective capacity of NGF during development and in normal and diseased tissues in adulthood and discuss the role of NGF in Alzheimer‘s disease and nociception. In addition, the role of NGF in processing sensory information and its influ |
出版日期 | Book 2021 |
关键词 | Brain; GDNF; Neurotrophic Factors; Neurotrophins; NGF, BDNF, NT3-4; Spinal cord; nerve growth factor |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-030-74046-7 |
isbn_softcover | 978-3-030-74048-1 |
isbn_ebook | 978-3-030-74046-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |