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Titlebook: Recent Advances in Clinical Trial Design and Analysis; Peter F. Thall Book 1995 Springer Science+Business Media New York 1995 AIDS.Anästhe

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发表于 2025-3-21 17:52:38 | 显示全部楼层 |阅读模式
书目名称Recent Advances in Clinical Trial Design and Analysis
编辑Peter F. Thall
视频videohttp://file.papertrans.cn/823/822648/822648.mp4
丛书名称Cancer Treatment and Research
图书封面Titlebook: Recent Advances in Clinical Trial Design and Analysis;  Peter F. Thall Book 1995 Springer Science+Business Media New York 1995 AIDS.Anästhe
描述Clinical trials have two purposes -- to treat the patients inthe trial, and to obtain information which increases our understandingof the disease and especially how patients respond to treatment.Statistical design provides a means to achieve both these aims, whilestatistical data analysis provides methods for extracting usefulinformation from the trial data. .Recent advances in statistical computing have enabled statisticians toimplement very rapidly a broad array of methods which previously wereeither impractical or impossible. Biostatisticians are now able toprovide much greater support to medical researchers working in bothclinical and laboratory settings. As our collective toolkit oftechniques for analyzing data has grown, it has become increasinglydifficult for biostatisticians to keep up with all the developments inour own field. .Recent Advances in Clinical Trial Design andAnalysis. brings together biostatisticians doing cutting-edgeresearch and explains some of the more recent developments inbiostatistics to clinicians and scientists who work in clinicaltrials.
出版日期Book 1995
关键词AIDS; Anästhesie-Informations-Management-System; data analysis; diagnostics; statistics
版次1
doihttps://doi.org/10.1007/978-1-4615-2009-2
isbn_softcover978-1-4613-5830-5
isbn_ebook978-1-4615-2009-2Series ISSN 0927-3042 Series E-ISSN 2509-8497
issn_series 0927-3042
copyrightSpringer Science+Business Media New York 1995
The information of publication is updating

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The exact analysis of contingency tables in medical research,zes are reasonably large and well balanced across the populations. For small, sparse, skewed, or heavily tied data, the asymptotic theory may not be valid. See Agresti and Yang [1] for some empirical results, and Read and Cressie [2] for a more theoretical discussion.
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Issues in the design and analysis of AIDS clinical trials,of clinical trial design and analysis, and the body of this chapter highlights a few of these. Before beginning, however, we consider the question of why it is necessary, or at least useful, to focus on advances in methodology for AIDS clinical trials.
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The alpha spending function approach to interim data analyses,Numerous clinical trials have been conducted during this period across a wide variety of diseases, evaluating drugs, procedures, devices, and biologic materials. The fundamentals of the design, conduct, and analyses of clinical trials have been developed and refined during this period as well. One s
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