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Titlebook: Rat Genomics; G. Thomas Hayman,Jennifer R. Smith,Mary Shimoyama Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 20

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发表于 2025-3-21 16:55:37 | 显示全部楼层 |阅读模式
书目名称Rat Genomics
编辑G. Thomas Hayman,Jennifer R. Smith,Mary Shimoyama
视频video
概述Includes cutting-edge techniques and vital background information.Provides detail essential for reproducible results in the lab.Contains key implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Rat Genomics;  G. Thomas Hayman,Jennifer R. Smith,Mary Shimoyama Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 20
描述This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project.  In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investigation or to leverage a new technology.  In other cases, a detailed review of existing models or a description of available resources can help the researcher find, understand, and utilize the information, the data, and the tools that they need to support their research efforts. Written as part of the highly successful .Methods in Molecular Biology. series, this collection includes the kind of hands-on detail necessary for success in the lab. .Authoritative and up-to-date, .Rat Genomics. explores the rat as a biomedical model uniquely poised to provide the ideal combination of established experimental models, extensive physiological data, and genomic manipulability to facilitate exploration of the underlying biology..
出版日期Book 2019
关键词Translational research; Genome editing; The microbiome; Exome sequencing; Human disease research; Hybrid
版次1
doihttps://doi.org/10.1007/978-1-4939-9581-3
isbn_softcover978-1-4939-9583-7
isbn_ebook978-1-4939-9581-3Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2019
The information of publication is updating

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Next Generation Transgenic Rat Model Production,f choice, to purify the microinjection reagents, to deliver the reagents to the eggs by pronuclear microinjection, to use the surgical transfer of microinjected eggs to pseudopregnant rats to obtain G0 founder animals that carry the novel genetic modification. Ultimately the success of new rat model
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Protocols for Cryopreservation and Rederivation of Rat Gametes,xt generation pups using embryo transfer and intracytoplasmic sperm injection (ICSI). In this chapter, we describe in detail protocols for rat embryo vitrification and sperm cryopreservation followed by pup rederivation using the ICSI procedure and embryo transfer.
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Fluorescent Imaging and Microscopy for Dynamic Processes in Rats,ly occurs at the objective focal plane, not above or below. Additionally, longer excitation wavelengths allow for deeper penetration into tissue, improved excitation, and are inherently less phototoxic than shorter excitation wavelengths. Applying imaging tools to study physiology in rats has become
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Genomic Research in Rat Models of Kidney Disease,s, focusing on the contribution of rat genetics and genomics to the elucidation of the mechanisms underlying the pathophysiology of the major types of renal disease, including primary and secondary renal diseases.
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Jennifer R. Smith,Elizabeth R. Bolton,Melinda R. Dwinellnd its collaborators ran a series of conferences to bring policymakers and scholars together and to provide new documentary evidence on the basis of which they could collectively attempt to reconstruct the important decisions that led to the end of the Cold War.
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