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Titlebook: Rabbit Biotechnology; Rabbit genomics, tra Louis-Marie Houdebine (Doctor),Jianglin Fan (Chair Book 2009 Springer Science+Business Media B.V

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书目名称Rabbit Biotechnology
副标题Rabbit genomics, tra
编辑Louis-Marie Houdebine (Doctor),Jianglin Fan (Chair
视频video
概述It is clear that with the progress of genome sequencing, ES cells culture, cloning, transgenesis and interfering RNAs and other techniques, rabbit biotechnology is entering a new era..It is a good tim
图书封面Titlebook: Rabbit Biotechnology; Rabbit genomics, tra Louis-Marie Houdebine (Doctor),Jianglin Fan (Chair Book 2009 Springer Science+Business Media B.V
描述Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.
出版日期Book 2009
关键词biological functions; biotechnology; cell lines; cloning; genes; genome; metabolism; genetic engineering
版次1
doihttps://doi.org/10.1007/978-90-481-2227-1
isbn_softcover978-90-481-8476-7
isbn_ebook978-90-481-2227-1
copyrightSpringer Science+Business Media B.V. 2009
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Derivation and Characterization of Rabbit Embryonic Stem Cells: A Review,mbryonic stem cells, germ cells, epiblast stem cells and induced pluripotent cells. The methods used for isolation of rabbit embryonic stem like cells and rabbit primordial germ cells are detailed in the second part, including the species specific factors playing role in the maintenance of pluripote
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Book 2009quires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is geneticall
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rabbit biotechnology is entering a new era..It is a good timLouis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified
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