书目名称 | Proteins and Proteomics of Leishmania and Trypanosoma |
编辑 | André L.S. Santos,Marta H. Branquinha,Cátia L. Sod |
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概述 | The book presents an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera.The book contains an updated review on the expression of biologically releva |
丛书名称 | Subcellular Biochemistry |
图书封面 |  |
描述 | This book contains a collection of critical reviews on the expression of biologically functional proteins in. Leishmania. and .Trypanosoma., which was written by renowned researchers on this field. Species belonging to these trypanosomatids’ genera are etiological agents of leishmaniasis, Chagas’ disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quiet unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by .Leishmania .and .Trypanosoma. by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategie |
出版日期 | Book 2014 |
关键词 | Chemotherapy; Leishmania; Protein; Proteomic; Trypanosoma; infectious diseases |
版次 | 1 |
doi | https://doi.org/10.1007/978-94-007-7305-9 |
isbn_softcover | 978-94-024-0749-5 |
isbn_ebook | 978-94-007-7305-9Series ISSN 0306-0225 Series E-ISSN 2542-8810 |
issn_series | 0306-0225 |
copyright | Springer Science+Business Media Dordrecht 2014 |