书目名称 | Protein Quality Control in Neurodegenerative Diseases |
编辑 | Richard I. Morimoto,Yves Christen |
视频video | |
概述 | Written by leading experts in the fields Neuroscience and Endocrinology.Provides topical research results.Another excellent group of authors and their chapters collected by Fondation Ipsen.Includes su |
丛书名称 | Research and Perspectives in Alzheimer‘s Disease |
图书封面 |  |
描述 | The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer‘s disease, Parkinson‘s disease, amyotrophic lateral sclerosis, Huntington‘s disease, and other diseases of protein conformation. |
出版日期 | Book 2013 |
关键词 | autophagy; cellular defense; cytoplasmic degradation; neuronal control; protein homeostasis |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-27928-7 |
isbn_softcover | 978-3-642-44706-8 |
isbn_ebook | 978-3-642-27928-7Series ISSN 0945-6066 Series E-ISSN 2196-310X |
issn_series | 0945-6066 |
copyright | Springer-Verlag Berlin Heidelberg 2013 |