| 书目名称 | Proteases in Apoptosis: Pathways, Protocols and Translational Advances | | 编辑 | Kakoli Bose | | 视频video | http://file.papertrans.cn/762/761553/761553.mp4 | | 概述 | Gives fundamental and exclusive information on all proteases involved in programmed cell death in a single compilation.Is an essential source of information in any biomedical scientist‘s library.Provi | | 图书封面 |  | | 描述 | .This book provides a comprehensive overview of the proteases involved in programmed cell death. It presents a focused yet extensive discussion on proteolytic enzymes such as caspases, HtrAs, granzymes, calpains and cathepsins as well as laboratory protocols related to enzymology and apoptosis. Mouse model systems and non-invasive imaging techniques in apoptosis-related diseases such as cancer and neurodegeneration are also covered in this book..While slowly unravelling the complexities of apoptosis in chapter one,. .the next three chapters individually elaborate on different classes of proteases that play key roles in the initiation, progression and execution of programmed cell death. The last two chapters complete this discussion by describing different laboratory methodologies and therapeutic advances involving apoptotic proteases. Protocols portraying .in vitro. and .ex vivo. colorimetric and fluorescence-based enzyme kinetic studies as well as cell death assays are explained in the fifth chapter. Preclinical .in vivo. models and non-invasive imaging in apoptosis to understand the complexities of disease progression and their contribution toward therapeutics is recounted in the | | 出版日期 | Book 2015 | | 关键词 | drug design; immune system; mouse model; programmed cell death; tissue homeostasis; Apoptosis | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-19497-4 | | isbn_softcover | 978-3-319-34677-9 | | isbn_ebook | 978-3-319-19497-4 | | copyright | Springer International Publishing Switzerland 2015 |
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