| 书目名称 | Prefoldins: the new chaperones |
| 编辑 | Nabil Djouder |
| 视频video | |
| 概述 | A comprehensive book on molecular chaperones of the prefoldin family Several contributions from top researches in the prefoldin field Dedicated section to the URI prefoldin-like complex |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease. This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined..This work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.. |
| 出版日期 | Book 2018 |
| 关键词 | prefoldin; Hsp90; URI; chaperones; prefoldin regulation; Protein Structure |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-00737-9 |
| isbn_ebook | 978-3-030-00737-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer Nature Switzerland AG 2018 |
发表于 2025-3-21 18:27:47
