| 书目名称 | Phosphoinositide 3-kinase in Health and Disease |
| 副标题 | Volume 1 |
| 编辑 | Christian Rommel,Bart Vanhaesebroeck,Peter K. Vogt |
| 视频video | |
| 概述 | PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone.The expectations for a therapeutic impact of intervention with PI3K activity are high, and |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here |
| 出版日期 | Book 2011 |
| 关键词 | PDK1; PI3K; TOR kinase domain inhibitor; haematological malignancies; malignant glioma; oncogenesis; oncop |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-13663-4 |
| isbn_softcover | 978-3-642-26522-8 |
| isbn_ebook | 978-3-642-13663-4Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
发表于 2025-3-21 17:15:31
