| 书目名称 | Phosphodiesterases: CNS Functions and Diseases |
| 编辑 | Han-Ting Zhang,Ying Xu,James M. O‘Donnell |
| 视频video | http://file.papertrans.cn/747/746351/746351.mp4 |
| 概述 | 30 internationally recognized experts on PDEs provide a comprehensive overview of their roles in the CNS.First book to cover all PDEs and their related neurological diseases and disorders.Authors sugg |
| 丛书名称 | Advances in Neurobiology |
| 图书封面 |  |
| 描述 | PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer‘s Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs. |
| 出版日期 | Book 2017 |
| 关键词 | Central Nervous System; Cyclic Nucleotides; Neurodegenerative Disease; Neuropsychiatric Disorders; Phosp |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-58811-7 |
| isbn_softcover | 978-3-319-86479-2 |
| isbn_ebook | 978-3-319-58811-7Series ISSN 2190-5215 Series E-ISSN 2190-5223 |
| issn_series | 2190-5215 |
| copyright | Springer International Publishing AG 2017 |
|Archiver|手机版|小黑屋|
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