书目名称 | Phenotypes and Genotypes |
副标题 | The Search for Influ |
编辑 | Florian Frommlet,Małgorzata Bogdan,David Ramsey |
视频video | |
概述 | Introduces the major concepts of Quantitative Trait Loci mapping.Discusses the methodology of Quantitative Trait Loci mapping in experimental populations.Describes the methods for Genome Wide Associat |
丛书名称 | Computational Biology |
图书封面 |  |
描述 | .Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes). The book provides a detailedreview of methods of gene mapping used in association with experimentalcrosses, as well as genome-wide association studies. Emphasis is placed onmodel selection procedures for analyzing data from large-scale genome scansbased on specifically designed modifications of the Bayesian informationcriterion. Features: presents a thorough introduction to the theoreticalbackground to studies of genetic association (both genetic and statistical); reviewsthe latest advances in the field; illustrates the properties of methods formapping quantitative trait loci using computer simulations and the analysis ofreal data; discusses open challenges; includes an extensive statisticalappendix as a reference for those who are not totally familiar with thefundamentals of statistics.. |
出版日期 | Book 2016 |
关键词 | Association Mapping; Genome Wide Association Studies (GWAS); Quantitative Trait Loci (QTL); Trait Loci |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4471-5310-8 |
isbn_softcover | 978-1-4471-7380-9 |
isbn_ebook | 978-1-4471-5310-8Series ISSN 1568-2684 Series E-ISSN 2662-2432 |
issn_series | 1568-2684 |
copyright | Springer-Verlag London 2016 |