| 书目名称 | Pharmacogenomics | | 副标题 | Methods and Protocol | | 编辑 | Federico Innocenti | | 视频video | http://file.papertrans.cn/746/745568/745568.mp4 | | 概述 | Includes supplementary material: | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions. | | 出版日期 | Book 2005 | | 关键词 | Allele; DNA; SNP; gene expression; genes; genetics; genomics; microarray; research | | 版次 | 1 | | doi | https://doi.org/10.1385/1592599575 | | isbn_softcover | 978-1-61737-571-2 | | isbn_ebook | 978-1-59259-957-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2005 |
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