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Titlebook: Parkinson’s Disease; Neurophysiological, Fathy S. Messiha (Associate Professor, Chairman),A Book 1977 The Editor(s) (if applicable) and Th

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Neurophysiology of Movement Disordersto the cortex will produce contralateral paralysis while damage to the basal ganglia or cerebellum will re sult in movement abnormalities. These data provide support for the view that subcortical but not cortical structures initiate and control movement activity. It would appear that the basal gangl
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Problems in the Treatment of Parkinsonismlso brought new sets of problems. The very effectiveness of levodopa therapy has modified the clinical spectrum of symptomatology. By suppressing tremor and rigidity and prolong ing our patients’ lives, we have uncovered other manifestations of parkinsonism which were previously less prominent. The
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The On-Off Effect in Parkinson’s Disease Treated with Levodopa with Remarks Concerning the Effect of Sleepng from this phenomenon increased rapidly the first three or four years with some continuing increase through out the six years of the study. Even those whose disease had worsened would become even more incapacitated during parts of each day. One group of patients experienced their initial “On” effe
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