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Titlebook: Osteoimmunology; Interactions of the Yongwon Choi Conference proceedings 2010 The Editor(s) (if applicable) and The Author(s), under exclu

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发表于 2025-3-21 17:29:35 | 显示全部楼层 |阅读模式
书目名称Osteoimmunology
副标题Interactions of the
编辑Yongwon Choi
视频video
概述Proceedings from the 2nd International Conference on Osteoimmunology: Interactions of the Immune and Skeletal Systems in Aldemar Paradise Village, June 8-13, 2008, Rhodes, Greece.Includes supplementar
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Osteoimmunology; Interactions of the  Yongwon Choi Conference proceedings 2010 The Editor(s) (if applicable) and The Author(s), under exclu
描述.It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells...In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference wil
出版日期Conference proceedings 2010
关键词apoptosis; bone marrow; cell; cytokine; cytokines; protein; proteins; infectious diseases
版次1
doihttps://doi.org/10.1007/978-1-4419-1050-9
isbn_softcover978-1-4614-2495-6
isbn_ebook978-1-4419-1050-9Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/o/image/704899.jpg
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https://doi.org/10.1007/978-1-4419-1050-9apoptosis; bone marrow; cell; cytokine; cytokines; protein; proteins; infectious diseases
发表于 2025-3-22 08:39:05 | 显示全部楼层
Regulation of Osteoclast Apoptosis by Bcl-2 Family Protein Bim and Caspase-3,aspase-3. Osteoclasts generated from . –/– mice exhibited a shorter life span and a higher bone-resorbing activity than those generated from normal littermates. These results suggest the important role of Caspase-3-Bim axis in regulating both apoptosis and activation of osteoclasts.
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978-1-4614-2495-6The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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,Activation of γδ T Cells by Bisphosphonates,re now being revealed. In addition to their anti-resorptive effects, it is now apparent that nitrogen-containing BPs (N-BPs) have immunomodulatory properties. Specifically, these drugs activate immune cells called gamma, delta T lymphocytes. In this chapter we discuss the mechanism of gamma, delta T
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Megakaryocyte-Bone Cell Interactions, that MKs can have significant effects on cells of the osteoclast (OC) and osteoblast (OB) lineage, with obvious manifestations on bone phenotype, and probable significance for human pathology..There are currently four mouse models in which increases in MK number lead to a specific bone pathology of
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