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Titlebook: Optical Imaging of Brain Function and Metabolism 2; Physiological Basis Arno Villringer,Ulrich Dirnagl Book 1997 The Editor(s) (if applica

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书目名称Optical Imaging of Brain Function and Metabolism 2
副标题Physiological Basis
编辑Arno Villringer,Ulrich Dirnagl
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Optical Imaging of Brain Function and Metabolism 2; Physiological Basis  Arno Villringer,Ulrich Dirnagl Book 1997 The Editor(s) (if applica
描述This volume covers the latest developments in optical imaging of the brain which is becoming an increasingly important functional neuroimaging method. Optical intrinsic signals offer unrivaled temporal and spatial resolution of functional measurements of the exposed brain cortex in animals and humans. Near-infrared spectroscopy and imaging ap­ proaches permit the noninvasive functional assessment of the human brain at bedside. Main advantages of these optical techniques are the biochemical specificity of the meas­ urements and the potential of measuring correlates of intracellular and intravascular oxy­ genation simultaneously. Recent data indicate that one may also measure a more direct correlate of neuronal activity associated with changes in light scattering. In this volume, recent technical progress of the optical method is covered as well as the physiological basis of the measurements. In simultaneous studies, near-infrared spec­ troscopy measurements are directly compared to other functional methods, especially PET and fMRI and examples are given for new applications of the NIRS-method. Based on re­ sults obtained with optical methods and other functional techniques the lates
出版日期Book 1997
关键词imaging; infrared spectroscopy; metabolism; optical imaging; spectroscopy
版次1
doihttps://doi.org/10.1007/978-1-4899-0056-2
isbn_softcover978-1-4899-0058-6
isbn_ebook978-1-4899-0056-2Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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978-1-4899-0058-6The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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The MR ,, Based Perfusion ModelThere are a number of theoretical and practical questions one needs to consider to understand and optimize contrast to noise of the versatile .. based perfusion model. We made an evaluation of the several popular .. based methods currently applied to measure flow and flow change.
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Towards Near-Infrared Imaging of the BrainSeveral methods have been employed in attempts to estimate atraumatically the in-vivo cerebral blood flow and metabolism. One approach is to measure brain hemoglobin oxygen-saturation level and blood volume in vivo by using near-infrared reflection or transmission spectroscopy.
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Is There a Different Type of MR-Contrast in the Early Phase of Functional Activation?ase in the oxyhemoglobin concentration of the activated areas, which can be observed by susceptibility sensitive MR imaging techniques such as echo planar imaging (2) or gradient echo imaging with long echo times (3).
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Cerebral Oxygenation States as Revealed by Near-Infrared Spectrophotometryitoring of tissue oxygenation. However, even now the quantification of hemoglobin signals and the knowledge of the redox behavior of cytochrome oxidase in vivo, as well as the measurement of cytochrome in the presence of normal blood circulation still pose unresolved issues.
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