书目名称 | Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy | 编辑 | Dale Jonathan Waterhouse | 视频video | | 概述 | Nominated as an outstanding Ph.D. thesis by the University of Cambridge, Cambridge, UK.Presents a comprehensive analysis of the common barriers and unique challenges associated with the clinical trans | 丛书名称 | Springer Theses | 图书封面 |  | 描述 | This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With conti | 出版日期 | Book 2019 | 关键词 | Optical Imaging of Cancer; Multispectral Endoscopy; Multispectral Imaging of Cancer; Clinical Translati | 版次 | 1 | doi | https://doi.org/10.1007/978-3-030-21481-4 | isbn_softcover | 978-3-030-21483-8 | isbn_ebook | 978-3-030-21481-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 | issn_series | 2190-5053 | copyright | Springer Nature Switzerland AG 2019 |
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