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Titlebook: Normal and Malignant Hematopoiesis; New Advances Enrico Mihich,Donald Metcalf Book 1995 Springer Science+Business Media New York 1995 Chrom

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书目名称Normal and Malignant Hematopoiesis
副标题New Advances
编辑Enrico Mihich,Donald Metcalf
视频video
丛书名称Pezcoller Foundation Symposia
图书封面Titlebook: Normal and Malignant Hematopoiesis; New Advances Enrico Mihich,Donald Metcalf Book 1995 Springer Science+Business Media New York 1995 Chrom
描述‘‘An exciting glance at key issues in contemporaryhematopoiesis.‘‘ -.The Quarterly Review of Biology.
出版日期Book 1995
关键词Chromosom; Pathogene; T cell; biology; cell; development; genes; hematopoiesis; hematopoietic stem cell; leuk
版次1
doihttps://doi.org/10.1007/978-1-4615-1927-0
isbn_softcover978-1-4613-5789-6
isbn_ebook978-1-4615-1927-0
copyrightSpringer Science+Business Media New York 1995
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Non-Receptor Protein Tyrosine Kinases, cognate ligand stimulates dimerization of the growth factor receptors in the membrane, and subsequent augmentation of phosphate transfer. Substrates for this kinase activity include the receptor molecules themselves, which when phosphorylated manifest binding sites for regulatory enzymes that stimu
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Positive and Negative Growth Effects of Abl Genes,eus and have identified Ras and Myc as essential proteins in the Bcr-Abl transformation pathway. We have also found that the normal c-Abl protein suppresses growth and that mutant proteins such as v-Abl and Bcr-Abl convert c-Abl from a growth suppressive to a transforming protein.
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Advances in the Understanding of the Molecular Pathogenesis of Aggressive B Cell Lymphomas, Motokura et al., 1991; Raffeid et al., 1991). In follicular-type NHL(FL), the t(14;18) translocation juxtaposes the IgH locus to BCL-2 (Bakhshi et al., 1985; Tsujimoto et al., 1984; Cleary et al., 1985), a gene coding for a protein that prevents programmed cell death or apoptosis (Korsmeyer, 1992).
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Contribution of the Cyclin D1 Gene to Lymphomagenesis,ar environment impinge on this basic cycling machinery. Another is how it is perturbed by oncogenic changes. Finally, the major issue addressed below is whether altered expression of a cycle component can itself contribute to oncogenesis.
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Donald Metcalfhe organism” (p. 292). The current work on the inseparability of cognition and affect, the affective nature of consciousness, and the relation between emotional development and the concept of self both lend support to this statement and attest to the inseparability of emotion from other modes of psychological function.
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