Titlebook: New Trends in Hepatology; The Proceedings of t Paolo Gentilini,Mario Umberto Dianzani Conference proceedings 1996 Kluwer Academic Publisher

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Possible Role of Ethanol-Derived Free Radicals in the Pathogenesis of Alcohol-Induced Liver Damageletely elucidated [1]. Acetaldehyde, the main product of ethanol oxidation, is generally considered to be main responsible for the damaging effects associated to alcohol abuse [1]. In recent years, however, an increasing number of studies have suggested that, beside acetaldehyde, free radical interm

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The Cellular and Molecular Basis of Liver Fibrogenesis multiple physiological and pathophysiological roles. In particular, several . and . studies have clearly indicated that HSC play a relevant role in the progression of liver fibrogenesis. More recently, the attention has been focused on the mechanisms leading to HSC activation, proliferation and syn

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Reoxygenation Injury in Isolated Rat Hepatocytesell injury. Mitochondria and microsomes but not the cytosolic xanthine oxidase system appear to be the main intracellular sources of free radical production. Lipids and proteins rather than DNA are damaged by oxygen free radicals during the early phases of post-anoxic reoxygenation. Finally, protein

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