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Titlebook: New Principles in Developmental Processes; Hisato Kondoh,Atsushi Kuroiwa Book 2014 Springer Japan 2014 cell competition.embryogenesis.hete

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Taxon-Specific Maternal Factors for Germline Specification repression of zygotic gene expression is conserved, participating components are often variable and taxon specific. Here I present our recent findings on germline development of the Japanese ascidian ., as an example of conserved genetic mechanisms that do not rely on conserved genes.
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Secondary Smad1/5/8-Dependent Signaling Downstream of SHH Determines Digit Identitynx-forming region (PFR) cells in a way reflecting the earlier SHH signaling. PFR is located immediately distal to the condensed cartilage of the digit primordium and serves as the zone of cartilage differentiation, and the differential strength of SMAD1/5/8 activation in the PFR was correlated with digit identity.
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Book 2014ology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes.  
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Cell Competition: The Struggle for Existence in Multicellular Communities such as stem cell regulation and cancer development. In this chapter, we discuss recent insights in cell competition. Elucidation of the mechanism by which cell competition is controlled could create a new dimension for understanding the basic principle of multicellular systems.
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Contribution of Apoptosis in Cranial Neural Tube Closure Indicated by Mouse Embryo Live Imagingcaspase activation interfered with and delayed the progression of NTC in the cranial region. The analysis also revealed existence of two types of apoptotic cells during NTC. Based on these results, we propose that cell removal by caspase-mediated apoptosis facilitates NTC and ensues the completion of NTC within a limited developmental time window.
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Limb Regeneration: Reconstitution of Complex Organs Using Specific Tissue Interactionsular description is not well established. Recently, a brand-new experimental system called an accessory limb model (ALM) was reported that is designed to reveal minimum and necessary tissue interaction including nerves. In this chapter, necessary tissue interactions for blastema induction in the ALM and related molecular descriptions are given.
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