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Titlebook: Neurotrophic Factors; Gary R. Lewin,Bruce D. Carter Book 2014 Springer-Verlag Berlin Heidelberg 2014 2014 BDNF.NGF.NT3.P75NTR.TrkA.pain.si

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书目名称Neurotrophic Factors
编辑Gary R. Lewin,Bruce D. Carter
视频video
概述The relevance of neurotrophins in a variety of diseases ranging from inflammatory pain, to neurodegeneration and metabolic disease is comprehensively reviewed.The successful pharmacological avenues us
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Neurotrophic Factors;  Gary R. Lewin,Bruce D. Carter Book 2014 Springer-Verlag Berlin Heidelberg 2014 2014 BDNF.NGF.NT3.P75NTR.TrkA.pain.si
描述This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.
出版日期Book 2014
关键词BDNF; NGF; NT3; P75NTR; TrkA; pain; signalling; sortilin
版次1
doihttps://doi.org/10.1007/978-3-642-45106-5
isbn_softcover978-3-662-52089-5
isbn_ebook978-3-642-45106-5Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 2014 2014
The information of publication is updating

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Neurotrophins: Transcription and Translationd synaptic function. Key functions of the neurotrophins rely on these proteins being expressed at the right time and in the right place. This is especially true for BDNF, stimulus-inducible expression of which serves as an essential step in the transduction of a broad variety of extracellular stimul
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BDNF and Synaptic Plasticity, Cognitive Function, and Dysfunctionynapses. It is now widely accepted that the main function of BDNF in the adult brain is to regulate synapses, with structural and functional effects ranging from short-term to long-lasting, on excitatory or inhibitory synapses, in many brain regions. The diverse effects of BDNF on brain synapses ste
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