| 书目名称 | Neurotoxicity of Aluminum | | 编辑 | Qiao Niu | | 视频video | | | 概述 | Reviewing the research development of aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease.Aluminum levels in brain, region and subcellular distribution, the relation to neurofibri | | 图书封面 |  | | 描述 | .This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment..The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and | | 出版日期 | Book 2023Latest edition | | 关键词 | Aluminum; Neurotoxicity; Cognitive impairment; Pathological features; Cell death; Alzheimer’s disease | | 版次 | 2 | | doi | https://doi.org/10.1007/978-981-99-1592-7 | | isbn_softcover | 978-981-99-1594-1 | | isbn_ebook | 978-981-99-1592-7 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
The information of publication is updating
|
|
发表于 2025-3-21 18:28:25
