| 书目名称 | Neurotoxicity of Aluminum |
| 编辑 | Qiao Niu |
| 视频video | |
| 概述 | reviewing the cutting-edge research development linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease.focusing on aluminum levels in brain, region-specific and subcellular d |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity. . |
| 出版日期 | Book 20181st edition |
| 关键词 | Aluminum; Neurotoxicity; Cognitive impairment; Pathological features; Cell death; Alzheimer’s disease |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-13-1370-7 |
| isbn_softcover | 978-981-13-4621-7 |
| isbn_ebook | 978-981-13-1370-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer Nature Singapore Pte Ltd. 2018 |
发表于 2025-3-21 18:18:15
