| 书目名称 | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) |
| 编辑 | Caroline Fonta,László Négyessy |
| 视频video | |
| 概述 | Offers a wealth of new information on alkaline phosphatase TNAP functions in the nervous system.Opens up new insights on the regulation of neural functions.A valuable resource for both researchers and |
| 丛书名称 | Subcellular Biochemistry |
| 图书封面 |  |
| 描述 | Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer‘s disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs. |
| 出版日期 | Book 2015 |
| 关键词 | Brain development; Cerebral cortex; Epilepsy; Metabolic disorders; Neurobiology |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-017-7197-9 |
| isbn_softcover | 978-94-024-0273-5 |
| isbn_ebook | 978-94-017-7197-9Series ISSN 0306-0225 Series E-ISSN 2542-8810 |
| issn_series | 0306-0225 |
| copyright | Springer Science+Business Media Dordrecht 2015 |
发表于 2025-3-21 17:03:51
