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Titlebook: Neuronal Death by Accident or by Design; Christopher E. Henderson,Douglas R. Green,Yves Chr Conference proceedings 2001 Springer-Verlag Be

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书目名称Neuronal Death by Accident or by Design
编辑Christopher E. Henderson,Douglas R. Green,Yves Chr
视频video
概述Includes supplementary material:
丛书名称Research and Perspectives in Neurosciences
图书封面Titlebook: Neuronal Death by Accident or by Design;  Christopher E. Henderson,Douglas R. Green,Yves Chr Conference proceedings 2001 Springer-Verlag Be
描述Four chapters represent the intense current effort to understand the way in which the mitochondrion controls the activation of the final stages of cell death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that will not only allow us to better understand what is happening in these patients but also, with luck, allow for development of more efficient and specific drugs in the future? Firstly, the concept of a central common cell death pathway, originally derived from studies on the nematode, has been an outstanding productive paradigm in bringing together different strands of research. Secondly, truly striking links have been made between results obtained in the culture dish (or even cell-free systems) and the diseased human brain.
出版日期Conference proceedings 2001
关键词Huntingdon‘s Disease; Neurodegeneration; Parkinson; Parkinson‘s Disease; apoptosis; motoneurons; neuronal
版次1
doihttps://doi.org/10.1007/978-3-662-04333-2
isbn_softcover978-3-642-07517-9
isbn_ebook978-3-662-04333-2Series ISSN 0945-6082 Series E-ISSN 2196-3096
issn_series 0945-6082
copyrightSpringer-Verlag Berlin Heidelberg 2001
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Research and Perspectives in Neuroscienceshttp://image.papertrans.cn/n/image/664264.jpg
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Christopher E. Henderson,Douglas R. Green,Yves ChrIncludes supplementary material:
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0945-6082 s the activation of the final stages of cell death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that will not only allow us to better understand what is happening in these pat
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Normal Programmed Cell Death of Developing Avian and Mammalian Neurons Following Inhibition or Geneet-dependent post-mitotic neurons. Neurons undergoing PCD in the absence of caspases exhibit a non-apoptotic, often TUNEL-negative, mode of morphological degeneration. Loss of caspase activity may delay but does not prevent the quantitatively normal occurrence of neuronal PCD.
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Bcl-2 Family Members and Permeabilization of the Outer Mitochondrial Membrane,hat cleave key intracellular substrates, resulting in the morphological and biochemical changes associated with apoptosis. Recently, it was found that, in many apoptotic responses, caspase activation is coordinated by mitochondria.
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Conference proceedings 2001l death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that will not only allow us to better understand what is happening in these patients but also, with luck, allow for develo
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