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Titlebook: Neuroendocrine Tumours; Diagnosis and Manage Suayib Yalcin,Kjell Öberg Book 2024Latest edition Springer Nature Switzerland AG 2024 Neuroend

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VIPoma and PPoma,sponding to an incidence of 0.01/100,000 yearly. Mostly located intrapancreatic in adults (mainly pancreatic tail). Some rare extra-pancreatic subtypes are present mainly in children. Median age of diagnosis is 54 years and 2–4 years in children, with a slight female predominance. VIPomas tend to gr
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Glucagonoma,rs often associated with a well-described glucagonoma syndrome characterized with hyperglucagonemia, skin rash, glucose intolerance, hypoalbuminemia, weight loss, and normochromic normocytic anemia. Glucagonomas may present as a part the multiple endocrine neoplasia syndrome type 1 (MEN 1). They are
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Somatostatinoma,ning and are detected either incidentally or by local mass effect symptoms, but active tumours can produce a spectrum of symptoms called ‘somatostatinoma syndrome’. Specific preoperative diagnosis for a somatostatinomas is difficult and may only reveal a NET; immunohistochemical staining for somatos
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Less Common Types of Pancreatic Neuroendocrine Tumors, in the gastroenteropancreatic system and the lungs. Although NETs are considered to be rare, there are even more rare subtypes of NETs. For example, functional pNETs represent less than 10% of pNETs. Their clinical behavior is very heterogenous with a changing disease course such as malignant tumor
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High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO 3),her well-differentiated low-grade (G1-G2) neuroendocrine tumors (NET) or poorly differentiated high-grade (G3) neuroendocrine carcinoma (NEC). NEN G3 have a proliferation rate (Ki67) above 20% or >20 mitoses 10 HPF. The 2017 WHO classification of pancreatic neuroendocrine tumors defined a new group
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Radiological Imaging,nd are discussed in Chapter 8. Cross-sectional imaging is valuable in the context of patient follow-up, for evaluating treatment response and in the detection of recurrent or metastatic disease. This chapter will describe the cross-sectional imaging techniques and appearances of NETs.
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