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Titlebook: Neuroendocrine Tumors in Real Life; From Practice to Kno Annamaria Colao,Antongiulio Faggiano,Wouter de Her Book 2018 Springer Internationa

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发表于 2025-3-21 16:53:13 | 显示全部楼层 |阅读模式
书目名称Neuroendocrine Tumors in Real Life
副标题From Practice to Kno
编辑Annamaria Colao,Antongiulio Faggiano,Wouter de Her
视频video
概述Approaches NETs from the perspective of clinical experience.Describes numerous clinical cases to illustrate all possible scenarios in terms of clinical presentation and course.Provides evidence-based
图书封面Titlebook: Neuroendocrine Tumors in Real Life; From Practice to Kno Annamaria Colao,Antongiulio Faggiano,Wouter de Her Book 2018 Springer Internationa
描述.This book on neuroendocrine tumors (NETs) aims to present, in a clear and innovative manner, a broad topic that is still unevenly and in some respects poorly delineated. The novel feature is the nature of the focus on the principles of prognosis, diagnosis, and therapy, which are outlined on the basis of well-defined clinical scenarios described with the aid of high-quality images and illustrations. The salient observations to emerge from the reported clinical cases are clearly summarized, taking into account evidence from the literature and the available guidelines. All of the significant prognostic factors – histopathological, molecular, and imaging – and current diagnostic and therapeutic strategies for the major NETs (stomach, pancreas, ileum, appendix, bronchus) are covered. In addition, in the introductory part of the book the reader will find information on basic aspects including epidemiology, classification, and underlying biological mechanisms. .Neuroendocrine Tumors inReal Life. will be of interest to all specialists involved in the management of NETs; it will provide the experienced with important updates and equip trainees and students with a firm understanding of key
出版日期Book 2018
关键词Incidence; clinical presentation; diagnosis; prognosis; therapy
版次1
doihttps://doi.org/10.1007/978-3-319-59024-0
isbn_softcover978-3-319-86534-8
isbn_ebook978-3-319-59024-0
copyrightSpringer International Publishing AG 2018
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发表于 2025-3-21 20:59:34 | 显示全部楼层
发表于 2025-3-22 03:00:49 | 显示全部楼层
Tumor Detection in Syndromic NET: Zollinger-Ellison Syndrome ZES was hypothesized on the basis of early age of onset and the evidence of multifocal tumors within the pancreas and duodenum, despite the absence of primary hyperparathyroidism. The diagnostic workup included endoscopic ultrasound, contrast-enhanced multi-detector computed tomography, and somatostatin-receptor scintigraphy.
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Tumor Staging: Bronchi systemic lymphadenectomy should be performed. Postoperative long-term clinical and radiological follow-up is mandatory, especially in case of biologically aggressive tumoral forms: local relapses or distant metastases are, in fact, reported even many years after the first operation.
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Prognostic Factors: Molecular Pathway – Oncogene (mTOR)nning the best therapeutic approach. Recently, the mammalian target of rapamycin (mTOR) pathway has emerged as an important therapeutic target for the medical treatment of NEN. We here review the available information on the prognostic value of mTOR pathway derangements in patients with NET.
发表于 2025-3-23 02:08:55 | 显示全部楼层
Prognostic Factors: Molecular Pathway – Tumour Suppressor Gene (MEN1)rather than evidence-based guidelines have been developed to optimize early tumour detection and management, but open issues remain. Yet, the follow-up of MEN1 patients in real life remains challenging, especially in young patients (<20 year), in whom there is increasing evidence of asymptomatic NETs.
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