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Titlebook: Neuroendocrine Perspectives; Proceedings of the T John A. H. Wass,Maurice F. Scanlon Conference proceedings 1989 Springer-Verlag New York I

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Introduction to neuroendocrine investigation. Very recently, specific nucleotide recognition sequences for thyroid hormones, steroid hormones and the fundamental intracellular regulator, cyclic AMP, have been determined. In this section, the preliminary characterization and investigation of the nuclear binding
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Regulation of Expression of the Human Pre-Provip Genehe last decade, a new endocrinology of intracellular communication has evolved. This new endocrinology addresses the pathways that transduce signals from the surface of the cell membrane to the nucleus. New techniques in molecular biology, coupled with recent insights into the biochemistry of signal
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Pituitary Growth Factorsh, induction of cell-specific unique proteins or regulation of a differentiated cell function (1). The latter function of growth factors is mediated by a direct regulation of phenotypic gene expression. The pituitary gland has been shown to contain increasing numbers of specific growth factors, most
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Mechanisms of Action of Growth Factorsy clear that one or more defects in the physiological mechanisms that regulate cell proliferation can be the cause of tumor cell growth. The study of normal cell division is therefore important not only per se, but especially in relation to its pathological implications.
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Neuropeptides and Neurotransmitters: Inositol Phospholipid and cAMP Responses in Cultured Brain Cellhomogenates. This procedure, however, does not allow differentiation between agonists and antagonists nor does it allow the underlying mechanisms involved in the ligand-receptor response to be investigated.
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Neuroendocrine Aspects of Cardiovascular Control: The Brain Renin-Angiotensin Systemhe complex homeostatic system. We plan to touch on aspects of the evolution of peptides, their genetics, synthesis and processing. The renin-angiotensin system will serve as an example of a well characterized enzyme-peptide system, which occurs both as a hormonal and as a neuropeptidergic system cle
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Endogenous Na+, K+-ATPase Inhibitors fluid volume (ECFV) expansion by saline infusion in dogs produced a marked increase in urinary sodium excretion (1). He showed that this was due to the presence of a circulating factor because blood from a ECFV-expanded dog could induce natriuresis in a recipient dog. The involvement of all known r
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