书目名称 | Neuroendocrine Neoplasia Management | 副标题 | New Approaches for D | 编辑 | Giordano Beretta,Alfredo Berruti,Orlando Goletti | 视频video | http://file.papertrans.cn/665/664010/664010.mp4 | 概述 | Presents novel approaches in the diagnosis and treatment of tumors of neuroendocrine origin.Examines strategies in the treatment of NEN according to therapy responsivity.Explores new perspectives in N | 图书封面 |  | 描述 | .This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptortreatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging res | 出版日期 | Book 2021 | 关键词 | Neuro Endocrine Neoplasia (NEN); Diagnosis and treatment; Predictive biomarkers; response to therapy; Bi | 版次 | 1 | doi | https://doi.org/10.1007/978-3-030-72830-4 | isbn_softcover | 978-3-030-72832-8 | isbn_ebook | 978-3-030-72830-4 | copyright | Springer Nature Switzerland AG 2021 |
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