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Titlebook: Neurodegenerative Disorders as Systemic Diseases; Keiji Wada Book 2015 Springer Japan 2015 Alzheimer’s disease.Biomarkers.Brain disorders.

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Tamami Fukushiations of biosignals. Although the material has been written and developed primarily for advanced undergraduate biomedical engineering students it will also be of interest to engineers and interested biomedical professionals of any discipline seeking an introduction to the field. Within education, m
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Conformational Disease and RNA Disease Theory in the Context of Neurodegenerative Diseasesst 30 years, the causative genes of many hereditary neurodegenerative diseases and the components of most of their characteristic inclusions have been identified. However, the molecular mechanisms responsible for neuronal degeneration have not been fully clarified. Here we review the history of neur
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Parkinson’s Disease; Neurodegeneration as Systemic Diseasecompanied by intraneuronal α-synuclein containing inclusions called “Lewy bodies.” Nowadays, PD can also be described as a heterogeneous multi-system neurodegenerative disease since α-synuclein deposits are not restricted to the central nervous system but also found in peripheral nerves. Braak stagi
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Clinical Systems Neuroscienceted to neurological, neurosurgical, and psychiatric disorders. Clinical systems neuroscience concerns neural functions as an operation of a system, not of a simple collection of elements. It deals with issues situated at the intersection between clinical practice and neuroscience at the system, cogn
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Genetic Risk Factors for Neurodegenerative Diseases neurodegenerative diseases that show a Mendelian pattern of inheritance, mutations in a major causative gene are solely responsible for the disease phenotype and underlying pathogenesis; whereas, the occurrence of more common neurodegenerative diseases likely requires the combined effect of alterat
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Drug Development for Neurodegenerative Diseases defined as a group of intractable disorders, which are characterized by the progressive degeneration of neurons in various regions of the brain, resulting in neurological and psychiatric symptoms. Molecular genetics and biological studies have revealed that most neurodegenerative diseases are cause
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