Titlebook: Neurodegenerative Diseases; Clinical Aspects, Mo Daniela Galimberti,Elio Scarpini Book 20141st edition Springer-Verlag London 2014 Alzheime

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,Alzheimer’s Disease: Clinical Aspects and Treatments,haracterized by short-term memory loss. Once the disease progresses, patients experience difficulties in sense of direction, oral communication, calculation, ability to learn, and cognitive thinking. In addition, patients may develop language deficits, depression, aggressive behavior, and psychosis

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,Autosomal Dominant Alzheimer’s Disease: Underlying Causes,far, genetic analyses of families with autosomal dominant AD, presenting with early-onset dementia (<65 years of age), have found three causal genes: ., ., and .. The possibility to detect carriers of causal mutations could help to evaluate the efficacy of different treatments at either asymptomatic

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,Nongenetic Risk Factors for Alzheimer’s Disease,ors for AD, including nutritional, social, and medical factors. Although many aspects of the disease are still unclear, some interesting hypotheses have been suggested to explain the role of exposures in its pathogenesis. At the moment it is also possible to delineate some preventive strategies for

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Frontotemporal Lobar Degeneration: Genetics and Clinical Phenotypes,havioral variant frontotemporal dementia (bvFTD), primary nonfluent aphasia (PNFA), semantic dementia (SD), and logopenic aphasia. In 2011, new diagnostic criteria bvFTD, which include the use of biomarkers, have been published. According to them, bvFTD can be classified into “possible” (clinical fe

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,Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia,ocesses in Alzheimer’s disease (AD) and frontotemporal dementia (FTD). These CSF biomarkers have been studied for diagnosis, prognosis, and treatment follow-up and in relation to genetics and neuroimaging. They are now increasingly used in research, drug development, and clinical settings to increas