Titlebook: Neuro-Geriatrics; A Clinical Manual Babak Tousi,Jeffrey Cummings Book 2017 Springer International Publishing AG 2017 neuro-geriatrics.neuro

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Jeffrey Cummings M.D., Sc.D.,Kate Zhong M.D. the rat somatostatin gene, we have determined the sequence of the gene isolated from recombinant bacteriophage libraries. The gene spans 1.2 kilobases in length and is interrupted within the coding sequence of prosomatostatin by a single intron of 630 bases. A variant of the Goldberg-Hogness promot

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Charles Bernick M.D., M.P.H.in brain and/or cerebrospinal fluid (CSF) of patients with several neuropsychiatric disorders, particularly Alzheimer’s disease and depression. These studies of SS in neuropsychiatric disorders will be reviewed in this chapter, as will the evidence supporting a role for SS as a modulator of CNS acti

interlude

Jeffrey Cummings M.D., Sc.D. neuronal areas of the gastrointestinal (GI) tract. There is selective processing of the SS precursor to yield different proportions of the two peptides, which may have different effects in different tissues or on specific functions. SS-14 appears to be the predominant form secreted by neuronal and

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Aaron Ritter M.D.,Jagan A. Pillai M.B.B.S, Ph.D.the synthetic peptide for research, it has been possible to demonstrate that both predictions were true. Subsequent work revealed that somatostatin, as initially isolated (somatostatin 14), was but one of several related peptides, part of a multigene family, with tissue specific processing. Many of the detail978-1-4684-5328-7978-1-4684-5326-3

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Kasia Gustaw Rothenberg M.D., Ph.D.,James B. Leverenz M.D.tic peptide for research, it has been possible to demonstrate that both predictions were true. Subsequent work revealed that somatostatin, as initially isolated (somatostatin 14), was but one of several related peptides, part of a multigene family, with tissue specific processing. Many of the detail

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Sarah J. Banks Ph.D.logy . . . Thereafter, however, the rewards are increasingly achieved by the application of high technology". Although one might argue whether this golden age is really foregone, and discuss the "height" of the technology involved, this quotation is closely related to the main motivations of Part II